Dr Saf completed his specialist training from University college London hospitals  UK in General Medicine Diabetes and Endocrinology. He was appointed a Consultant Endocrinologist at Ashford & St Peters Hospital in London in 2002 and worked as a Consultant until January 2013 when he moved to Abu Dhabi. In UK Dr Saf  has headed diabetes care in intermediate and  secondary care settings. He was instrumental in setting up a consultant led diabetes intermediate care service  for Hounslow and Richmond primary care trust in 2011 in the west London area.

Dr Saf moved to Abu Dhabi in January 2013 and started working as a Consultant Endocrinologist and vice chairman medical Board at the Imperial college London Diabetes Centre (ICLDC).  In 2014 he was appointed as Medical Director of ICLDC and remained in this role till March 2020. During his tenure ICLDC expanded its network to three branches , achieved the status of centre of excellence by the international Diabetes federation and  In addition had the best patient experience in the gulf region and with a  public health campaign reaching to over a million people. The clinical quality outcomes exceeded all international bench marks during his tenure. He is now working as a senior consultant Endocrinologist at ICLDC.

Dr Saf has also served  as an honorary consultant Endocrinologist at imperial Health care UK and member of the ICL/ICLDC Research and education Board. He has been a member of the Research, Education and innovation and quality and patient safety committees with representations from Cleveland Clinic and Imperial college London.